They said in the commentary for 04/22 that Dean's comments to Zachariah about being human:
Dean: You can take your peace... and shove it up your lily-white ass. 'Cause I'll take the pain and the guilt. I'll even take Sam as is. It's a lot better than being some Stepford bitch in paradise.
is his redemption for "I wish I didn't have to feel, Sammy". Of course, this doesn't mean that Dean's perhaps ultimate wish is for...nothing. Time and time again on the show they have shown that Dean is not a taker and perhaps too much of a giver. And perhaps that is his secret. What does he hunger for that Famine can give him? Nothing. He wants Sam to be safe. He wants to not be Michael's vessel. He wants to avert the Apocalypse. He has his dream car. He's happy going from conquest to conquest. He can have whatever food he wants.
And, maybe, also, he is getting some help from Death? Death wants Dean et alia to beat Lucifer, and if anyone could deaden wants and needs I expect that would be Death.
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Dean: You can take your peace... and shove it up your lily-white ass. 'Cause I'll take the pain and the guilt. I'll even take Sam as is. It's a lot better than being some Stepford bitch in paradise.
is his redemption for "I wish I didn't have to feel, Sammy". Of course, this doesn't mean that Dean's perhaps ultimate wish is for...nothing. Time and time again on the show they have shown that Dean is not a taker and perhaps too much of a giver. And perhaps that is his secret. What does he hunger for that Famine can give him? Nothing. He wants Sam to be safe. He wants to not be Michael's vessel. He wants to avert the Apocalypse. He has his dream car. He's happy going from conquest to conquest. He can have whatever food he wants.
And, maybe, also, he is getting some help from Death? Death wants Dean et alia to beat Lucifer, and if anyone could deaden wants and needs I expect that would be Death.